The word(s) "sign" appears 351 time(s) in 320 verse(s) in Quran in Mohsin Khan translation.

(71) And to (the people of) Madyan (Midian), (We sent) their brother Shu'aib. He said: "O my people! Worship Allah! You have no other Ilah (God) but Him. [La ilaha illallah (none has the right to be worshipped but Allah)]." Verily, a clear proof (sign) from your Lord has come unto you; so give full measure and full weight and wrong not men in their things, and do not do mischief on the earth after it has been set in order, that will be better for you, if you are believers.

(72) Then after them We sent Musa (Moses) with Our signs to Fir'aun (Pharaoh) and his chiefs, but they wrongfully rejected them. So see how was the end of the Mufsidun (mischief-makers, corrupters).

(73) [Fir'aun (Pharaoh)] said: "If you have come with a sign, show it forth, if you are one of those who tell the truth."

(74) "And you take vengeance on us only because we believed in the Ayat (proofs, evidence, lessons, signs, etc.) of our Lord when they reached us! Our Lord! pour out on us patience, and cause us to die as Muslims."

(75) They said [to Musa (Moses)]: "Whatever Ayat (proofs, evidence, verses, lessons, signs, revelations, etc.) you may bring to us, to work therewith your sorcery on us, we shall never believe in you."

(76) So We sent on them: the flood, the locusts, the lice, the frogs, and the blood (as a succession of) manifest signs, yet they remained arrogant, and they were of those people who were Mujrimun (criminals, polytheists, sinners).

(77) So We took retribution from them. We drowned them in the sea, because they belied Our Ayat (proofs, evidence, verses, lessons, signs, revelations, etc.) and were heedless about them.

(78) I shall turn away from My Ayat (verses of the Qur'an) those who behave arrogantly on the earth, without a right, and (even) if they see all the Ayat (proofs, evidence, verses, lessons, signs, revelations, etc.), they will not believe in them. And if they see the way of righteousness (monotheism, piety, and good deeds), they will not adopt it as the Way, but if they see the way of error (polytheism, crimes and evil deeds), they will adopt that way, that is because they have rejected Our Ayat (proofs, evidence, verses, lessons, signs, revelations, etc.) and were heedless (to learn a lesson) from them.

(79) Those who deny Our Ayat (proofs, evidence, verses, lessons, signs, revelations, etc.) and the Meeting in the Hereafter (Day of Resurrection,), vain are their deeds. Are they requited with anything except what they used to do?

(80) "And ordain for us good in this world, and in the Hereafter. Certainly we have turned unto You." He said: (As to) My punishment I afflict therewith whom I will and My Mercy embraces all things. That (Mercy) I shall ordain for those who are the Muttaqun (the pious - See V.2:2), and give Zakat; and those who believe in Our Ayat (proofs, evidence, verses, lessons, signs and revelations, etc.);