The word(s) "sign" appears 351 time(s) in 320 verse(s) in Quran in Mohsin Khan translation.

(311) Verily, those who oppose Allah and His Messenger (Muhammad صلى الله عليه وسلم) will be disgraced, as those before them (among the past nation) were disgraced. And We have sent down clear Ayat (proofs, evidence, verses, lessons, signs, revelations, etc.). And for the disbelievers is a disgracing torment.

(312) The likeness of those who were entrusted with the (obligation of the) Taurat (Torah) (i.e. to obey its commandments and to practise its laws), but who subsequently failed in those (obligations), is as the likeness of a donkey which carries huge burdens of books (but understands nothing from them). How bad is the example of people who deny the Ayat (proofs, evidence, verses, signs, revelations) of Allah. And Allah guides not the people who are Zalimun (polytheists, wrong-doers, disbelievers).

(313) That was because there came to them their Messengers with clear proofs (signs), but they said: "Shall mere men guide us?" So they disbelieved and turned away (from the truth). But Allah was not in need (of them). And Allah is Rich (Free of all needs), Worthy of all praise.

(314) But those who disbelieved (in the Oneness of Allah - Islamic Monotheism) and denied Our Ayat (proofs, evidence, verses, lessons, signs, revelations, etc.), they will be the dwellers of the Fire, to dwell therein forever. And worst indeed is that destination .

(315) Nay! Verily, he has been opposing Our Ayat (proofs, evidence, verses, lessons, signs, revelations).

(316) Verily, it (Hell, or their denial of Prophet Muhammad صلى الله عليه وسلم, or the Day of Resurrection) is but one of the greatest (signs).

(317) For what Day are these signs postponed?

(318) But they belied Our Ayat (proofs, evidence, verses, lessons, signs, revelations, and that which Our Prophet صلى الله عليه وسلم brought) completely.

(319) Then [Musa (Moses)] showed him the great sign (miracles).

(320) But those who disbelieved in Our Ayat (proofs, evidence, verses, lessons, signs, revelations, etc.), they are those on the Left Hand (the dwellers of Hell).