The word(s) "sign" appears 351 time(s) in 320 verse(s) in Quran in Mohsin Khan translation.

(251) And an Ayah (sign) for them is that We bore their offspring in the laden ship [of Nuh (Noah)].

(252) And never came an Ayah from among the Ayat (proofs, evidence, verses, lessons, signs, revelations, etc.) of their Lord to them, but they did turn away from it.

(253) And when they see an Ayah (a sign, or an evidence) from Allah, they mock at it.

(254) And the leaders among them went about (saying): "Go on, and remain constant to your alihah (gods)! Verily, this is a thing designed (against you)!

(255) Is one who is obedient to Allah, prostrating himself or standing (in prayer) during the hours of the night, fearing the Hereafter and hoping for the Mercy of his Lord (like one who disbelieves)? Say: "Are those who know equal to those who know not?" It is only men of understanding who will remember (i.e. get a lesson from Allah's signs and Verses).

(256) It is Allah Who takes away the souls at the time of their death, and those that die not during their sleep. He keeps those (souls) for which He has ordained death and sends the rest for a term appointed. Verily, in this are signs for a people who think deeply.

(257) Do they not know that Allah enlarges the provision for whom He wills, and straitens it (for whom He wills). Verily, in this are signs for the folk who believe!

(258) Yes! Verily, there came to you My Ayat (proofs, evidence, verses, lessons, signs, revelations, etc.) and you denied them, and were proud and were among the disbelievers.

(259) To Him belong the keys of the heavens and the earth. And those who disbelieve in the Ayat (proofs, evidence, verses, signs, revelations, etc.) of Allah, such are they who will be the losers.

(260) None disputes in the Ayat (proofs, evidence, verses, lessons, signs, revelations, etc.) of Allah but those who disbelieve. So let not their ability of going about here and there through the land (for their purposes) deceive you [O Muhammad صلى الله عليه وسلم, for their ultimate end will be the Fire of Hell]!