The word(s) "what" appears 597 time(s) in 511 verse(s) in Quran in Muhammad Pickthal translation.

(161) Is it (only) then, when it hath befallen you, that ye will believe? what! (Believe) now, when (until now) ye have been hastening it on (through disbelief)?

(162) Then will it be said unto those who dealt unjustly Taste the torment of eternity. Are ye requited aught save what ye used to earn?

(163) Say: In the bounty of Allah and in His mercy: therein let them rejoice. It is better than what they hoard.

(164) Say: Have ye considered what provision Allah hath sent down for you, how ye have made of it lawful and unlawful? Hath Allah permitted you, or do ye invent a lie concerning Allah?

(165) And what think those who invent a lie concerning Allah (will be their plight) upon the Day of Resurrection? Lo! Allah truly is Bountiful toward mankind, but most of them give not thanks.

(166) And thou (Muhammad) art not occupied with any business and thou recitest not a Lecture from this (Scripture), and ye (mankind) perform no act, but We are Witness of you when ye are engaged therein. And not an atom's weight in the earth or in the sky escapeth your Lord, nor what is less than that or greater than that, but it is (written) in a clear Book.

(167) what! Now! When hitherto thou hast rebelled and been of the wrong-doers?

(168) Say: Behold what is in the heavens and the earth! But revelations and warnings avail not folk who will not believe.

(169) what expect they save the like of the days of those who passed away before them? Say: Expect then! I am with you among the expectant.

(170) Lo! now they fold up their breasts that they may hide (their thoughts) from Him. At the very moment when they cover themselves with their clothing, Allah knoweth that which they keep hidden and that which they proclaim. Lo! He is Aware of what is in the breasts (of men).